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10 hours ago · Nature Enhancer and super-enhancer dynamics in repair after is
2020年7月7日 · The endogenous repair process can result in recovery after acute kidney injury ( AKI) with adaptive proliferation of tubular epithelial cells, but ...
Herein we establish the enhancer and super-enhancer landscape after AKI by ChIP-seq in uninjured and repairing kidneys ... Access to this full-text is provided by Springer Nature. ... dynamics after kidney injury, affects critical repair responses.
2020年7月7日 · The endogenous repair process can result in recovery after acute kidney injury ( AKI) with adaptive proliferation of tubular epithelial cells, but ...
Nature. Author manuscript; available in PMC 2015 Nov 21. ... either in vitro or in wound-repair, HFSCs dynamically remodel super-enhancers in response to changes ... Dynamic super-enhancer remodeling facilitates lineage progression ... We were drawn to SOX9, since Sox9 was the only HFSC-TF gene that maintained a ...
The term 'super-enhancer' was first used in 2004 by Chen and colleagues to ... (3 kb), SEs are discriminated from other enhancers in a parameter-free manner after ... and could rapidly facilitate the establishment and maintenance of cell identity. ... super-enhancer dynamics in stem cell plasticity and lineage choice. Nature.
In genetics, a super-enhancer is a region of the mammalian genome comprising multiple ... expression. Super-enhancers have been since identified near cell identity-regulators in a range of mouse and human tissues. ... "Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice". Nature.
Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury, Nature Communications 11, July 2020. Joe Bonventre, Takaharu Ichimura  ...
The endogenous repair process can result in recovery after acute kidney injury ( AKI) with adaptive proliferation of tubular epithelial cells, but repair can also lead  ...
2019年10月15日 · At these super-enhancers the transcription factor TEAD4, together with ... transcription and repair mechanisms at oncogenic super-enhancers, ... These clusters appear in four non-treated replicates and also after ... Mapping and analysis of chromatin state dynamics in nine human ... Nature, 473 (2011), pp.
2019年4月5日 · Loss of superenhancer-regulated circNfix promotes cardiac regenerative repair and functional recovery after myocardial infarction by ... govern super-enhancer dynamics in stem cell plasticity and lineage choice.Nature. 2015 ...