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the most known high-risk genes

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Three of the most well-known genes that can mutate and raise the risk of breast and/or ovarian cancer are BRCA1, BRCA2, and PALB2.2020年6月26日
https://www.breastcancer.org › genetic

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由 C Wendt 著作2019被引用 35 次 — Heritage is the most important risk factor for breast cancer. ... of the highly penetrant autosomal dominant susceptibility genes ... a considerable amount of common low penetrance loci.
由 S Shiovitz 著作2015被引用 265 次 — This paper will review the known genetic causes of breast cancer and discuss the issues ... Most notably, there is an increased risk of ovarian cancer, with an estimated lifetime risk of 10–40% for ...
2020年11月19日 — A fact sheet about the BRCA1 and BRCA2 genes, what to do if a ... genes have increased risks of several cancers—most ... Are harmful variants in BRCA1 and BRCA2 more common in ...
Topics for People at Higher Risk of Breast Cancer ... Inherited gene mutations known to increase the risk of breast cancer are ... BRCA1 and BRCA2 (BReast CAncer genes 1 and 2) are the most well-known genes linked to breast cancer risk.
Home · Health A-Z · Live Well · Mental health · Care and support · Pregnancy · NHS services ... If you or your partner have a high-risk cancer gene, such as an altered version of ... This type of testing is known as predictive genetic testing.

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2018年9月3日 — They are known to increase breast cancer risk. It is unclear if the risk of ovarian cancer is increased.
由 ET Rosenthal 著作2017被引用 26 次 — In total, 9,751 PVs in the selected breast cancer risk genes were identified in 9,641 women. ... risk for female breast cancer to age 70 years, as well as increased risks for ... Patients known to have had previous testing for any of the genes in the ...
由 M Abu-Helalah 著作2020 — Breast cancer is the most common cancer in females worldwide contributing to 25.4% of the total ...
2019年9月10日 — These make your risk of breast cancer higher. ... These gene mutations are much less common, and most of them do not increase the risk of breast cancer as much as the BRCA genes.

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